Dent sickness is an extraordinary X-related recessive inherited condition that impacts the proximal renal tubules of the kidney. It is one cause of Fanconi syndrome, and is characterized with the aid of tubular proteinuria, excess calcium within the urine, formation of calcium kidney stones, nephrocalcinosis, and persistent kidney failure. Dent disease is often used to describe a whole group of familial disorders, including X-linked recessive nephrolithiasis with kidney failure, X-connected recessive hypophosphatemia rickets. The maximum frequent hint of Dent ailment is the presence of an abnormally massive amount of proteins inside the urine (tubular proteinuria).